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Innovative Concepts of Dual-Species Proton/Carbon Medical Synchrotrons


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Abstract


Hospital-based facilities offering treatments with low-LET and high-LET particles delivered by a common particle accelerator (LET = Linear Energy Transfer) are one of the recent trends in ion therapy. Protons and carbon ions are considered to be the best particle species for low-LET and high-LET treatments, respectively. Innovative concepts of proton/carbon medical synchrotrons based on the acceleration of molecular hydrogen ions for generation of protons are presented in the paper. These concepts do not compromise the medical requirements, but they are expected to bring several major advantages concerning the design, operation and cost of the accelerator: (1) shrinking the overall magnetic beam rigidity span of extracted beams, (2) reducing the space charge of a hydrogen beam at the injection, (3) a compact dual-species injector layout and (4) making a charge-exchange extraction technique at FFAG (Fixed Field Alternating Gradient) synchrotrons possible. Further potential advantages concern the power supplies (especially the ripple), field quality of the bending magnets and time structure of the extracted spills.
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Keywords


FFAG; Ion Therapy; Medical Accelerator; Synchrotron

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References


A. Brahme, R. Lewensohn, U. Ringborg, U. Amaldi, F. Gerardi, S. Rossi, Design of a Center for Biologically Optimized Light Ion Therapy in Stockholm, Nucl. Inst. and Meth. in Physics Research B184 (2001), 569-588.

E. Griesmayer, T. Schreiner, M. Pavlovic, The MedAustron Project, Nucl. Inst. and Meth. in Physics Research B258 (2007), 134-138.

P. J. Bryant (ed.) et al, Proton-Ion Medical Machine Study (PIMMS): Part I, CERN/PS 99-010 (DI) (CERN, Geneva, 1999) and Part II, CERN/PS 2000-007 (DR) (CERN, Geneva, 2000).

H. Eickhoff, T. Haberer, B. Schlitt, U. Weinrich, HICAT – The German Hospital-Based Light Ion Cancer Therapy Project, Proceedings of the 9th European Particle Accelerator Conference EPAC2004, Lucerne, Switzerland, 5-9 July 2004, 290 (2004)

M. Incurvati et al, The Italian Hadrontherapy Center (CNAO): a Review of the Power Supply System for Conventional Magnets, Proceedings of the 10th European Particle Accelerator Conference EPAC2006, Edinburgh, Scotland, 26-30 June 2006, 2676 (2006)

S. Yamada: The Progress on HIMAC and Particle Therapy Facilities in Japan, Proceedings of the 2nd Asian Particle Accelerator Conference APAC2001, Beijing, China, 17-21 September 2001, 829 (2001)

W. T. Chu, B. A. Ludewigt, T. A. Renner, Instrumentation for Treatment of Cancer Using Proton and Light-Ion Beams, Rev. Sci. Instrum. 64 (1993), 2055-2122.

K. Onosovsky, Ion Accelerators for Therapy, In: U. Amaldi, B. Larsson (eds.), Hadrontherapy in Oncology, Proceedings of the 1st International Symposium on Hadrontherapy, Como, Italy, 18-21 October 1993, 241 (Elsevier, Amsterdam-Lausanne-New York-Oxford-Shannon-Tokyo, 1994).

P. J. Bryant, M. Regler, M. Schuster (eds.), The AUSTRON Feasibility Study (Vienna, 1994).

T. Auberger, E. Griesmayer (eds.), Das Projekt MedAustron, second ed. (Fotec – Forschungs- und Technologietransfer GmbH, Wiener Neustadt, 2007).

R. Little, Initial Operation of the LLUMC Accelerator and Beam Transport, Nucl. Inst. and Meth. in Physics Research B56-57 (1991), 1192-1196.

T. Furukawa et al, Design of Synchrotron and Transport Line for Carbon Therapy Facility and Related Machine Study at HIMAC, Proceedings of the 7th International Conference on Accelerator Applications AccApp2005, Nucl. Inst. and Meth. in Physics Research A562, 1050-1053 (2006)

L. Calabretta, G. Cuttone, M. Maggiore, M. Re, D. Rifuggiato, A Novel Superconducting Cyclotron for Therapy and Radioisotope Production, Nucl. Inst. and Meth. in Physics Research A562 (2006), 1009-1012.

G. Kraft, Tumortherapy with Ion Beams, Nucl. Inst. and Meth. in Physics Research A454 (2000), 1-10.

J. Debus, K. D. Gross, M. Pavlovic (eds.), Proposal for a Dedicated Ion Beam Facility for Cancer Therapy, Joined Proposal of University of Heidelberg, German Cancer Research Center and GSI Darmstadt (GSI Darmstadt, 1998).

U. Amaldi, M. Silari (eds.), The TERA Project and the Center for Oncological Hadrontherapy, Feasibility Study (Blue Book) (INFN-LNF, SIS-Ufficio Publicazioni, Frascati (Roma), 1994).

U. Amaldi et al, The Italian Project for a Hadrontherapy Centre, Nucl. Inst. and Meth. in Physics Research A360 (1995), 297-301.

R. L. Martin, A Proton Accelerator for Medical Applications, Proceedings of the 9th International Conference on the Application of Accelerators in Research and Industry, Nucl. Inst. and Meth. in Physics Research B24-25, 1087 (1987)

V. S. Koroshkov et al, A Soviet Project of PTF, In: A. Itano, T. Kanai (eds.), Proceedings of the NIRS International Workshop on Heavy Charged Particle Therapy and Related Subjects, NIRS-M-81, 204 (Chiba, 4-5 July 1991)

B. Schlitt, K. Dermati, G. Hutter et al, Status of the 7 MeV/u 217 MHz Injector LINAC for the Heidelberg Cancer Therapy Facility, Proceedings of the XXIInd International Linear Accelerator Conference LINAC2004, Lübeck, Germany, 16-20 August 2004, 51 (2004)

G. Zschornack, S. Landgraf, F. Grossmann, U. Kentsch, V. P. Ovsyannikov, M. Schmidt, F. Ullmann, Dresden EBIT: the Next Generation, Nucl. Inst. and Meth. in Physics Research B235 (2005), 514-518.

G. Zschornack, F. Grossmann, V. P. Ovsyannikov, E. Griesmayer, Dresden EBIS-SC - A New Generation of Powerful Ion Sources for Medical Particle Therapy, Poster at the PTCOG 46 Meeting, Wanjie Proton Therapy Centre, Zibo, Shandong, China, 18-23 May 2007 & http://www.dreebit.com/

U. Kentsch, S. Landgraf, M. Schmidt, G. Zschornack, F. Grossmann, V. P. Ovsyannikov and F. Ullmann, X-ray Spectroscopy and Ion Extraction at the Dresden EBIT, Nucl. Inst. and Meth. in Physics Research B205 (2003), 260-265.

S. Rossi, Developments in Proton and Light-Ion Therapy, Proceedings of the 10th European Particle Accelerator Conference EPAC2006, Edinburgh, Scotland, 26-30 June 2006, 3631 (2006)

G. Rees, Presentation at the “Gantry Workshop 2007”, 9-10 March 2007, Vienna, Austria, (2007).

D. Solivajs, O. N. Borisov, A. Gall, G. G. Gulbekian, J. Keníž, J. Kliman, S. Králik, M. Pavlovič, A Study of Charge-Exchange Beam Extraction from the Multi-Purpose Isochronous Cyclotron DC-72, Journal of Electrical Engineering, 55 (2004), 201-206.


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