Electrodialysis and its Applications in Biotechnology

Towan Kikhavani(1*), Seyed Nezameddin Ashrafizadeh(2)

(1) Research Lab for Advanced Separation Processes, Department of Chemical Engineering, Iran University of Science and Technology, Narmak, Tehran 16846-13114, Iran., Iran, Islamic Republic of
(2) Research Lab for Advanced Separation Processes, Department of Chemical Engineering, Iran University of Science and Technology, Narmak, Tehran 16846-13114, Iran., Iran, Islamic Republic of
(*) Corresponding author


DOI's assignment:
the author of the article can submit here a request for assignment of a DOI number to this resource!
Cost of the service: euros 10,00 (for a DOI)

Abstract


Electrodialysis (ED) is an electrically-driven membrane process that can separate charged species across ion-exchange membranes. ED is an environmentally friendly technique which has been widely used in different applications. This process can be used as an integrated process with chemical, membrane, and biochemical unit operations. The integration of ED with biochemical processes has been used as its new applications, i.e. separation of biochemicals, production of organic acids from fermentation broths, and etc. In this review, the basic principles of ED, different configurations of the electrochemical ED cell, and its advantages and limitations are explained and discussed. Various applications of ED in bioprocesses have been thoroughly reviewed. Eventually, the research works required for the development and implementation of ED in bioprocesses are addressed and proposed
Copyright © 2012 Praise Worthy Prize - All rights reserved.

Keywords


Electrodialysis; Biochemical Process; Ion Exchange Membrane; Fermentation

Full Text:

PDF


References


M. Mulde, Basic Principles of Membrane Technology (Kluwer Academic Publishers Netherlands, 1996, pp. 380-390).

T. Xu, Ion exchange membranes: State of their development and perspective, J Membrane Sci. 263 (2005) 1-29.

J. U. Rype, Modeling of Electrically Membrane Processes, Ph.D dissertation, Dept. Chem. Eng., Denmark Technical Univ., 2002.

G. E. Molau, Heterogeneous ion-exchange membranes, J Membrane Sci. 8 (1981) 309-330.

R. K. Nagarale, G. S. Gohil, V. K. Shahi, Recent developments on ion-exchange membranes and electro-membrane processes, Adv Colloid Interface Sci. 119 (2006) 97-130.

Y. Tanaka, Ion exchange membranes: Fundamentals and Application (Elsevier, 2007).

N. P. Berezina, N. A. Kononenko, O. A. Dyomina, N. P. Gnusin, Characterization of ion-exchange membrane materials: properties vs structure, Adv in Colloid Interface Sci. 139 (2008) 3-28.

T. Xu, Electrodialysis Processes with Bipolar Membranes in Environmental Protection, Resources Conserv Recycl. 37 (2002) 1-22.

S. Sridhar, Electrodialysis in a non-aqueous medium: production of sodium methoxide, J Membrane Sci. 113 (1996) 73-79.

[10] H. Meng D. Deng, Sh. Chen, G. Zhang, A new method to determine the optimal operating current (Ilim) in the electrodialysis Process. Desalination 181: 101108 (2005).

H. J. Lee, H. Strathmann, S. H. Moon, Determination of the limiting current density in electrodialysis desalination as an empirical function of linear velocity, Desalination 190 (2006) 43–50.

[Y. Tanaka, Current density distribution and limiting current density in ion-exchange membrane electrodialysis, J. Membrane Sci. 173 (2000) 179–190.

V. Geraldes, M. D. Afonso, Limiting current density in the electrodialysis of multi-ionic solutions, J. Membrane Sci. 360 (2010) 499–508.

Ch. Huang, T. Xu, Y. Zhang, Y. Xue, G. Chen, Application of electrodialysis to the production of organic acids: State-of-the-art and recent developments, J Membrane Sci. 288 (2007) 1-14.

T. Chakrabarty, A. M. Rajesh, A. Jasti, A. K. Thakur, A. K. Singh, S. Prakash, V. Kulshrestha, V. K. Shahi, Stable ion-exchange membranes for water desalination by electrodialysis, Desalination 282 (2011) 2-8.

Q. Wang, T. Ying, T. Jiang, D. Yang, M. M. Jahangir, Demineralization of soybean oligosaccharides extract from sweet slurry by conventional electrodialysis, J Food Eng 95 (2009) 410-415.

M. Groot, A. Bos, A. Lazaro, R. Rooij, G. Bargeman, Electrodialysis for the concentration of ethanolamine salts, J Membrane Sci. 371 (2011) 75-83.

Y. Gong, Y. Tang, X. Wang, L. Yu, D. Liu, The possibility of the desalination of actual 1,3-propanediol fermentation broth by electrodialysis, Desalination 161(2004) 169-178.

M. Sadrzadeh, A. Razmi, T. Mohammadi, Separation of monovalent, divalent and trivalent ions at various operating conditions by electrodialysis, Desalination 205 (2007) 53-61.

X. Tongwen, Y. Weihua, Effect of cell configurations on the performance of citric acid production by a bipolar membrane electrodialysis, J Membrane Sci. 203 (2002) 145-153.

R. M. Bisselink, J. Erkel, Recovery of monoethanolamine by electro-electrodialysis, Permea 2010, Slovak Society of Chem. Eng., Tatranské Matliare, Slovakia, pp 764-771, 2010

Z. Wang, Y. Luo, P. Yu, Recovery of organic acids from waste salt solutions derived from the manufacture of cyclohexanone by electrodialysis, J Membrane Sci. 280 (2006) 134-137.

K. Belafibako, N. Nemestothy, L. Gubicza, A study on applications of membrane techniques in bioconversion of fumaric acid to malic acid, Desalination 162 (2004) 301-306.

S. Koter, Separation of weak and strong acids by electro-electrodialysis—Experiment and theory, Sep Purif Technol 60 (2008) 251-258.

C. Mazrou, H. Kerdjoudj, A. T. Chearif, Sodium Hydroxide and Hydrochloric Acid Generation from Sodium Chloride and Rock Salt by Electro-electrodialysis, J Appl Electrochem. 27 (1997) 558-567.

S. Frenzel, H. Holdik, D. F. Stamatialis, G. Pourcelly, M. Wessling, Chromic acid recovery by electro-electrodialysis: I. Evaluation of anion-exchange membrane, J Membrane Sci. 261 (2005) 49-57.

S. S. Yi, Y. Lu, G. Luo, Separation and concentration of lactic acid by electro-electrodialysis, Sep Purif Technol. 60 (2008) 308-314.

N. Tanaka, T. Yamaki, M. Asano, Y. Maekawa, K. Onuki, Electro-electrodialysis of HI–I2–H2O using radiation-grafted polymer electrolyte membranes, J Membrane Sci. 346 (2010) 136-142.

J. Wood, J. Gifford, J. Arba, M. Shaw, Production of ultrapure water by continuous electrodeionization, Desalination 250 (2010) 973-976.

N. Widiasa, P. D. Sutrisna, I. G. Wenten, Performance of a novel electrodeionization technique during citric acid recovery, Sep Purif Technol. 39 (2004) 89-97.

T. V. Eliseeva, V. A. Shaposhnik, E. V. Krisilova, A. E. Bukhovets, Transport of basic amino acids through the ion-exchange membranes and their recovery by electrodialysis, Desalination 241 (2009) 86-90.

Q. Li, C. Huang, T. Xu, Alcohol splitting for the production of methyl methoxyacetate: Integration of ion-exchange with bipolar membrane electrodialysis, J Membrane Sci.367 (2011) 314-318.

K. Zhang, M. Wang, C. Gao, Tartaric acid production by ion exchange resin-filling electrometathesis and its process economics, J Membrane Sci. 366 (2011) 266-271.

J. H. Choi, Sh. Kim, Sh. Moon, Recovery of lactic acid from sodium lactate by ion substitution using ion-exchange membrane, Sep Purif Technol. 28 (2002) 69-79.

N. Boniardi, R. Tota, G. Nano, B. Mazza, Lactic Acid Production by Electrodialysis. Part I. Experimental Tests, J Appl Elelctrochem. 27 (1997) 125-133.

Q. H. Wang, G. S. Cheng, X. H. Sun, Recovery of Lactic Acid from Kitchen Garbage Fermentation Broth by Four-Compartment Configuration Electrodialyzer, Process Bioche. 41 (2006) 152-158.

M. Moresi, F. Sappino, Economic feasibility study of citrate recovery by electrodialysis, J Food Eng. 35 (1998) 75-90.

G. S. Luo, J. G. Liu, Y. C. Lu, S. Pan, J. D. Wang, Two-Phase Electro-Electrodialysis with an Emulsion as Anolyte, Sep Sci Technol. 39 (2004) 1267-1278.

G. S. Luo, X. Y. Shan, X. Qi, Y. C. Lu, Two-phase electro-electrodialysis for recovery and concentration of citric acid, Sep Purif Technol. 38 (2004) 265-271.

Y. C. Lu, S. Yi, G. Luo, Modeling of the mass transfer and conduction behavior in electro-electrodialysis with oil/water emulsion as catholyte, J Membrane Sci. 322 (2008) 265-274.

S. Yi, Y. C. Lu, G. S. Luo, An in situ coupling separation process of electro-electrodialysis with back-extraction, J Membrane Sci. 255 (2005) 57-65.

F. Zhang, Ch. Huang, T. Xu, Production of Sebacic Acid Using Two-Phase Bipolar Membrane Electrodialysis, Ind Eng Chem Research. 48 (2009) 7482-7488.

S. Cattoir, D. Smets, A. Rahier, The use of electro-electrodialysis for the removal of sulphuric acid from decontamination effluents, Desalination 121 (1999) 123-130.

M. Kameche, F. Xu, C. Innocent, G. Pourcelly, Electrodialysis in water-ethanol solutions: Application to the acidification of organic salts, Desalination 154 (2003) 9-15.

L. Bazinet, F. Lamarche, D. Ippersiel, Bipolar-Membrane Electrodialysis: Applications of Electrodialysis in the Food Industry, Trends Food Sci Technol. 9 (1998) 107-113.

T. Xu, Ch. Huang, Electrodialysis-Based Separation Technologies: A Critical Review, AIChE J 54 (2008) 3147-3159.

A.Elmidaoui, M. A. Sahli, M. Tahaik, L. Chay, M. Taky, M. Elmgharib, M. Hafsi, Selective nitrate removal by coupling electrodialysis and a bioreactor, Desalination 153 (2002) 389-397.

J. Franc¸ O. Poulin, J. Amiot, L. Bazinet, Improved peptide fractionation by electrodialysis with ultrafiltration membrane: Influence of ultrafiltration membrane stacking and electrical field strength, J Membrane Sci. 299 (2007) 83-90.

J. Urbanus, R. J. M. Bisselink, K. Nijkamp, J. H. Horst, D. Verdoes, C. P. M. Roelands, Integrated product removal of slightly water-soluble carboxylates from fermentation by electrochemically induced crystallization, J Membrane Sci. 363 (2010) 36-47.

D. Bar, The Eurodia industries bipolar membrane electrodialysis unit for the conversion of sodium acetate into reusable acetic acid and caustic soda: more than five years of successful operation (Membrane Sep. Technol. News 2006).

G. Pourcelly, C. Gavach, Electrodialysis water splitting  application of electrodialysis with bipolar membranes, in: Handbook on Bipolar Membrane Technology, (Twente University Press, Netherlands, 2000, pp. 17–46).

N. Cicek, A Review of Membrane Bioreactors and their Potential Application in the Treatment of Agricultural Wastewater, Canadian Bio sys Eng. 45 (2003) 637-649.

Z. F.Cui, H. S. Muralidhara, Membrane Technology: A particular Guide to Membrane Technology and Applications in Food and Bio-processing (Elsevier Ltd., 2010, PP. 121-153).

F. Carstensen, A. Apel, M. Wessling, In situ product recovery: Submerged membranes vs. external loop membranes, J Membrane Sci. 394– 395 (2012) 1-36.

M. Pradhan, S. Vigneswaran, J. Kandasamy, R. Aim, Combined effect of air and mechanical scouring of membranes for fouling reduction in submerged membrane reactor, Desalination 288 (2012) 58-65.

W. Yang, N. Cicek, J. Ilg, State-of-the-art of membrane bioreactors: Worldwide research and commercial applications in North America, J Membrane Sci. 270 (2006) 201-211.

S. A. Ataei, E. V. Farahani, In-situ Separation of Lactic Acid from Fermentation Broth using Ion Exchange Resins, J Ind Microb Biotechnol. 35 (2008) 1229-1233.

[58] B. Kim, Y. Hong, W. H. Hong, Effect of Salts on the Extraction Characteristics of Succinic Acid by Pre-dispersed Solvent Extraction, Biotechnol Bioprocess Eng. 9 (2004) 207-211.

P. V. Iyer, Y. Y. Lee, Simultaneous Saccharification and Extractive Fermentation of Lignocellulosic Materials into Lactic Acid in a Two-Zone Fermentor-Extractor System, Appl Biochem Biotechnol 78 (1999) 409-419.

R. Jeantet, J. Maubois, P. Boyaval, Semi-continuous Production of Lactic Acid in a Bioreactor Coupled with NF Membranes, Enzym Microbial Technol. 19 (1996) 614-619.

H. Li, R. Mustacchi, Ch. Knowles, W. Skibar, G. Sunderland, I. Dalrymple, S. A. Jackman, An Electrokinetic Bioreactor: Using Direct Electric Current for Enhanced Lactic Acid Fermentation and Product Recovery, Tetrahedron 60 (2004) 655-661.

V. Magne, M. Amounas, C. Innocent, E. Dejean, Enzyme textile for removal urea: enzymatic reaction and electrodialysis, Desalination 144 (2002) 163-166.

T. Godjevargova, R. Dayal, S. Turmanova, Macromol biosci. 4 (2004) 950-957.

P. Boyaval, C. Cohre, S. Terre, Continuous Lactic Acid Fermentation with Concentrated Product Recovery by Ultrafiltration and Electrodialysis, Biotechnol Lett. 9 (1987) 207-212.

E. G. Lee, S. Kang, H. H. Kim, Y. K. Chang, Recovery of Lactic Acid from Fermentation Broth by the Two-Stage Process of Nanofiltration and Water Splitting Electrodialysis, Biotechnol Bioprocess Eng. 11 (2006) 313-318.

G. M. Tian, M. Koide, R. Gotou, H. Takanashi, M. Hirata, T. Hano, Development Continuous Electrodialysis Fermentation System for Production of Lactic Acid by Lactobacillus Rhamnosus Process Biochem. 40 (2005) 1033-1036.

Y. Nomura, M. Iwahara, M. Hongo, Acetic Acid Production by an Electrodialysis Fermentation Method with a Computerized Control System, Applied and Environmental Appl Environ Microbiol. 54 (1988) 137-142.

Y. Nomura, M. Iwahara, M. Hongo, Novel Method of Lactic Acid Production by Electrodialysis Fermentation, Acetic Acid Production by an Electrodialysis Fermentation Method with a Computerized Control System Appl Environ Microbiol. 52 (1986) 314-319.

P. Boontawan, S. Kanchanathawee, A. Boontawan, Extractive fermentation of lactic acid by Pediococcus pentosaceus using electrodeionization (EDI), e Biochem Eng J. 54 (2011) 192-199.

P. Pinacci, M. Radaelli, Recovery of citric acid from fermentation broths by electrodialysis with bipolar membranes, Desalination 148 (2002) 177-179.

M. Wong, J. M. Woodley, G. J. Lye, Enhanced Recombinant Protein Expression in Batch and Fed-Batch Escherichia Coil Fermentation Based on Removal of Acetate by Electrodialysis, J Chem Tech Biotechnol. 84 (2009) 1284-1291.

M. Wong, J. M. Woodley, G. J. Lye, Application of Bipolar Electrodialysis to E. Coil Fermentation for Simultaneous Acetate Removal and pH Control, Biotechnol Lett. 32 (2010) 1053-1057.

B. Zelir, D. V. Racki, Process development and modeling of pyruvate recovery from a model solution and fermentation broth, Desalination 174 (2005) 267-276.

O. A. Pradorubio, S. B. Jorgensen, G. Jonsson, Reverse Electro-Enhanced Dialysis for lactate recovery from a fermentation broth, J Membrane Sci. 374 (2011) 20-32.

L. Xuemei, L. Jianping, L. Mo'e, C. Peilin, L-lactic Acid Production Using Immobilized Rhizopus Oryzae in a Three-Phase Fluidized-Bed with Simultaneous Product Separation by Electrodialysis, Bioprocess Biosys Eng. 20 (1999) 231-237.

J. Y. Shen, J. R. Duan, X. H. Xing, P. Xu, Desalination of glutamine fermentation by electrodialysis, Process Biochem 41(2006) 716-720.

H. Danner, L. Madzingaidzo, C. Thomasser, M. Neureiter, R. Braun, Thermophilic Production of Lactic Acid Using Integrated Membrane Bioreactor Systems Coupled with Monopolar Electrodialysis, Appl Microbiol Biotechnol 59 (2002) 160-169.

Y. Nomura, J. Hallsworth, M. Iwahara, T. Tanaka, A. Ishizaki, Rapid and Effcient Production of lactate from Xylose using Electrodialysis Culture-Associated Product Separation, World J of Microbiol Biotechnol. 14 (1998) 911-916.

P. J. Moon, S. Parulekar, Sh. Tsai, Competitive anion transport in desalting of mixtures of organic acids by batch electrodialysis, J Membrane Sci. 141 (1998) 75-89.

J. Weier, B. A. Glatz, Ch. Glatz, Recovery of Propionic and Acetic Acids from Fermentation Broth by Electrodialysis, Biotechnol Prog. 8 (1992) 479-485.

F. A. Peretti, M. M. Silveira, M. Zeni, Use of electrodialysis technique for the separation of lactobionic acid produced by Zymomonas mobilis, Desalination 245 (2009) 626-630.

H. Lee, S. Oh, Sh. Moon, Recovery of ammonium sulfate from fermentation by electrodialysis, Water Res. 37 (2003) 1091-1099.

Ch. Casademont, P. Sistat, B. Ruiz, G. Pourcelly, L. Bazinet, Electrodialysis of model salt solution containing whey proteins: Enhancement by pulsed electric field and modified cell configuration, J Membrane Sci. 328 (2009) 238-245.

K. Zhang, M. Wang, D. Wang, C. Gao, The energy-saving production tartaric acid using ion exchange resin-filling bipolar membrane electrodialysis, J Membrane Sci. 341 (2009) 246-251.

L. Bazinet, D. Ippersiel, B. Mahdavi, Innov Food Sci Emer Technol 5 (2004) 17-25.

T. V. Eliseeva, V. A. Shaposhnik, I. G. Luschik, Demineralization and separation of amino acids by electrodialysis with ion-exchange membranes, Desalination 149 (2002) 405-409.

M. Kumar, B.P. Tripathi, V. K. Shahi, Electro-membrane process for the separation of amino acids by iso-electric focusing, J Chem Technol Biotechnol. 85 (2010) 648-657.

J. Shen, J. Duan, Y. Liu, Y. Lixin, X. Xing, Demineralization of glutamine fermentation broth by electrodialysis, Desalination 172 (2005) 129-135.

Y. Gong, Y. Tang, X. Wang, L. Yu, D. Liu, The possibility of the desalination of actual 1,3-propanediol fermentation broth by electrodialysis, Desalination 161 (2004)169-178.

M. T. Groot, A. C. M. Bos, A. P. Lázaro, R. M. Rooij, G. Bargeman, Electrodialysis for the concentration of ethanolamine salts, J Membrane Sci. 371 (2011) 75-83.

N. Boniardi, R. Rota, G. Nano, B. Mazz, Analysis of the sodium lactate concentration process by electrodialysis, Sep Technol. 6 (1999) 43-54.

M. L. Lameloise, H. Matinier, C. Fargues, Concentration and purification of malate ion from a beverage industry waste water using electrodialysis with homopolar membranes, J Membrane Sci. 343 (2009) 73-81.

M. A. Menkouchi, M. Tahaikt, I. Achary, M. Taky, F. Elhanouni, M. Hafsi, M. Elmghari, A. Elmidaoui, Technical optimization of nitrate removal for groundwater by ED using a pilot plant Original, Desalination 189 (2006) 200-208.

C. Wisniewski, F. Persin, T. Cherif, R. Sandeaux, A. Grasmick, C. Gavach, Denitrification of drinking water by the association of an electrodialysis process and a membrane bioreactor: feasibility and application, Desalination 139 (2001) 199-205.

C. Matos, A. Sequeira, S. Velizarov, J. Crespo, Nitrate removal in closed marine system through ion exchange membrane bioreactor, J. Hazardous Materials. 166 (2009) 428-434.

S. Velizaro, M. Areis, J. G. Crespo, Water purification and management (Springer, Netherlands, 2011, pp. 119146).

A. Bouchoux, H. R. Balmann, F. Lutin, Investigation of nanofiltration as a purification step for lactic acid production processes based on conventional and bipolar electrodialysis operations, Sep Purif Technol. 52 (2006) 266-273.

V. Habova, K. Melzoch, M. Rychtera, B. Sekavova, Electrodialysis as a useful technique for lactic acid separation from model solution and a fermentation broth, Desalination 162 (2004) 361-372.

H. Habe, Y. Shimada, T. Fukuoka, D. Kitamoto, M. Itagaki, K. Watanabe, H. Yanagishita, K. Sakaki, Two-stage electrodialytic concentration of glyceric acid from fermentation broth, J Biosci Bioeng. 110 (2010) 690-695.

Y. Wang, X. Zhang, T. Xu, Integration of conventional electrodialysis and electrodialysis with bipolar membranes for production of organic acids, J Membrane Sci. 365 (2010) 294-301.

M. Makoto Hirata, M. T. Gao, E. Toorisaka, H. Takanashi, T. Hano, Production of lactic acid by continuous electrodialysis fermentation with a glucose concentration controller, Biochemical Eng J. 25 (2005) 159-163.

M. Bailly, Production of organic acids by bipolar electrodialysis: realizations and perspectives, Desalination 144 (2002) 157-162.

M. Aider, D. Halleux, L. Bazinet, Trends Food Sci Technol. 19 (2008) 351-362.

A. Saxena, B.P. Tripathi, M. Kumar, V.K. Shahi, Membrane-based techniques for the separation and purification of proteins: an overview, Adv Colloid Interface Sci. 145 (2009) 1-22.

S. Galier, H. Balmann, Electrophoretic Membrane Contactors, Chem Eng Research. 83 (2005) 268-275.

L. Bazinet, L. Firdaous, Membrane processes and devices for separation of bioactive peptides, Recent Patents on Biotechnology 3 (2009) 61-72.

A.Doyen, L. Beaulieu, L. Saucier, Y. Pouliot, L. Bazinet, Impact of ultrafiltration membrane material on Peptide separation from a snow crab byproduct hydrolysate by electrodialysis with ultrafiltration membranes, J. Agric. Food Chem. 59 (2011) 1784-1792.

L. Doyen, L. Beaulieu, Y. Saucier, L. Pouliot, Demonstration of in vitro anticancer properties of peptide fractions from a snow crab by-products hydrolysate after separation by electrodialysis with UF membranes, Sep Purif Technol. 78 (2011) 321-329.

M. Aidera, S. Brunet, L. Bazinet, Effect of solution flow velocity and electric field strength on chitosan oligomer electromigration kinetics and their separation in an electrodialysis with ultrafiltration membrane (EDUF) system, Sep Purif Technol. 69 (2009) 63-70.

J. Poulin, J. Amiot , L. Bazinet, Simultaneous separation acid and basic bioactive peptides by electrodialysis ultrafiltration membrane, J of Biotechnol. 123 (2006) 314-328.

N. Soulet, H. Balmann, N. Sanchez, Continuous flow isoelectric focusing for purification of proteins, Electrophoresis 19 (1998) 1294-1299.

S. Novalic, T. Kongbangkerd, K. Kulbe, Recovery of Organic Acids with high Molecular Weight Using a Combined Electrodialytic Process, J Membrane Sci. 166 (2000) 99-104.


Refbacks

  • There are currently no refbacks.



Please send any question about this web site to info@praiseworthyprize.com
Copyright © 2005-2020 Praise Worthy Prize