Peptide Deformylase Inhibitors for Addressing the Issue of Bacterial Resistance


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Abstract


Peptide Deformylase (PDF) is an attractive antibacterial target, and is gaining much momentum in contemporary research because of its remarkable features. This article reviews the bacterial PDF structure and criteria required for designing novel PDF inhibitors. It also presents a summary of the known and recently explored classes of PDF inhibitors, both peptidic and non-peptidic
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Keywords


Non-Peptidic Inhibitors; Peptide Deformylase (PDF); Peptidic Inhibitors

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References


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